PATENTS AND REGULATORY EXCLUSIVITIES ON FDA-APPROVED INSULIN PRODUCTS: A LONGITUDINAL DATABASE STUDY, 1986-2019.

Patents and regulatory exclusivities on FDA-approved insulin products: A longitudinal database study, 1986-2019.

BackgroundInsulin is the primary treatment for type 1 and some type 2 diabetes but remains costly in the United States, even though it was discovered more than a VITAMIN C RADIANCE CITRUS FACIAL PEEL century ago.High prices can lead to nonadherence and are often sustained by patents and regulatory exclusivities that limit competition on brand-name

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A Traffic Flow Simulation Framework for Learning Driver Heterogeneity from Naturalistic Driving Data using Autoencoders

This paper proposes a novel data-centric framework for microscopic traffic flow simulation with intra and inter driver heterogeneity.We utilized a naturalistic driving corpus of 46 different drivers to learn and model the behavior divergence of Japanese drivers.First, ego-driver behavior signals are used to extract unique features of each driver wi

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